OPINION ON THE RISK QUANTIFICATION FOR CJD TRANSMISSION VIA SUBSTANCES OF HUMAN ORIGIN Adopted by The Scientific Committee on Medicinal Products and Medical Devices
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چکیده
In the mid-1990s, the spread of Bovine Spongiform Encephalopathy (BSE) to epidemic proportions in the United Kingdom created considerable concern among national and Community health and agriculture authorities. This worry was exacerbated in 1996 when the Creutzfeldt-Jakob Disease Surveillance Unit in Edinburgh identified a new variant of the disease (nvCJD) that exhibited characteristics linking it to BSE infected animals. Given compelling indications that BSE and nvCJD were caused by the same infectious agent, it was surmised that the probable cause was ingestion of bovine products containing the causative organism of BSE in cattle.
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